ND: |
ME08767975 |
PMID: |
8767975 |
LR: |
20061115 |
CED: |
19961023 |
DCO: |
19961023 |
Autoren: |
Giordano N; Nardi P; Senesi M; Palumbo F; Battisti E; Gonnelli S; Franci B; Campagna MS; Gennari C |
Titel: |
Efficacia e tollerabilità della glucosamina solfato nel trattamento della gonartrosi. The efficacy and safety of glucosamine sulfate in the treatment of gonarthritis |
Quelle: |
La Clinica terapeutica; VOL: 147 (3); p. 99-105 /199603/ |
PM: |
Print |
SU: |
IM |
Sprache: |
Italian |
CY: |
ITALY |
JID: |
0372604 |
ISSN: |
0009-9074 |
CO: |
CLTEA4 |
Institution: |
Istituto di Patologia Speciale Medica, Università degli Studi di Siena. |
DT: |
Comparative Study; English Abstract; Journal Article |
Schlagwörter |
CT: |
ADULT; AGED; AMINO ACIDS/*therapeutic use; AMINO SUGARS/*therapeutic use; DRUG THERAPY, COMBINATION; DRUG TOLERANCE/*; FEMALE; GLUCOSAMINE/*therapeutic use; HUMANS; MIDDLE AGED; OSTEOARTHRITIS/*drug therapy; TREATMENT OUTCOME |
CTG: |
ERWACHSENER; ALTE MENSCHEN; AMINOSÄUREN/*therapeutische Anwendung; AMINOZUCKER/*therapeutische Anwendung; ARZNEIMITTEL-KOMBINATIONSTHERAPIE; ARZNEIMITTELTOLERANZ/*; WEIBLICH; GLUCOSAMIN/*therapeutische Anwendung; MENSCH; MENSCHEN IM MITTLEREN LEBENSALTER; OSTEOARTHROSE/*Arzneimitteltherapie; BEHANDLUNGSERGEBNIS |
TE: |
Amino Acids; Amino Sugars; Glucosamine/3416-24-8; pyridinoline/63800-01-1 |
CR: |
3416-24-8; 63800-01-1 |
AB: |
This study was performed to evaluate the therapeutic efficacy and tolerability of glucosamine sulfate in patients with gonarthritis. During the 12-month study period, the signs and symptoms of the disease were evaluated, as well as the dosage of the urinary pyridinoline. In this trial, we demonstrated that glucosamine sulfate has a chondroprotective activity, which was significant after the first 3 months of therapy. Moreover, this study showed that the side effects due to glucosamine sulfate were mild to moderate and did not require discontinuation of the drug. |